Nomenclature

Nomenclature思维导图，主要包括：Primary和nucleophilicity两部分内容，希望对你有所帮助。

Nomenclature

• Primary?
  • primary, secondary, tertiary, quantinary
  • means the degree of substitution
  • for N
    • ammine
  • or functional group connected C
    • Alkyl halide
    • alcohol
  • or C it self
• nucleophilicity
  • defination
    • nucleophilicity
      • the affinity of a lewis base for a carbon atom in the Sn2 reaction
    • basicity
      • affinity of a base for a proton
  • factors effect it
    • roughly parallels basicity
    • usually increases going down a column of the periodic table
      • larger shell with electrons hold less tight
    • Negatively charged nucleophiles are usually more reactive than neutral one
      • So SN2 usually carried under basic condations
      • e.x. carboxylate ion, alkoxide ion
  • leaving group's strength
    • fastest leaving group stabalize negative charge best under transition state
    • most equilibira favored leaving group stabalize negative charge best after it leaves
      • means it's the weakest base the anion formed
      • determine wheather the reaction can happen
• It usually the same
  • weakest base can leave
    • -OH not likely to leave because it produce -OH which is very basic
    • -OH2+ can leave because producing water which is weak basidic