Internal causes: the variation of protooncoges and oncogenes
external cause
Physical carcinogenic factors
Chemical carcinogenic factors
Viral carcinogenic factors
property
Cell growth and division lose control
It is invasive and diffusive
Intercellular interactions change
Protein expression lineage or protein activity changes
The mRNA transcription lineage changes, and the nucleyotype changes
cell differentiation
Concept: After the same cell division, it gradually appears in morphological structure and physiological function, and the process of producing different cell taxa is called cell differentiation
Essentially: Results of gene-selective expression
discriminate
Cell division causes increased cell numbers
Cell differentiation causes increased cell types
Cell versatility
The differentiated cells in plants can still develop the potential of complete new plants under suitable conditions
Animal nuclei are also versatile
Cause: The differentiated cells have all the genetic material that develops into a complete new individual
Factors affecting cell differentiation
Effects of extracellular signaling molecules on cell differentiation
Cell memory and decision
The ects of fertilized egg cytoplasm on cell differentiation
Intercellular interactions and location effects
The environmental impact on gender
Chromatin changes and gene rearrangement
stem cells
All-potent stem cells: A fertilized egg
Multifunctional stem cells
unipotent stem cell
tumor stem cell
Tumor: The result of the gradual accumulation of gene mutations
